Research and Development: Productivity Assessment

A Panel Discussion Among Experts on R&D Productivity

August 2007

Deliverables:  Transcript

Study Description and Objectives

§    Determine the current state of pharmaceutical R&D and expected trends in the strength of the resulting pipeline

§    Assess factors contributing to the success rate of the R&D success

§    Determine where improvement possible:

o        Discovery: in-licensing and partnerships

o        Clinical trials completion

§         Use of validated surrogate endpoints; focus on personalized medicine

§         Adaptive trial design

§         Outsourcing to CROs, globally (e.g., Asia)

§         Technology, e.g., e-enabled technologies in the clinical research process

o        Regulatory submission and approval: likelihood of the FDA policy changes, e.g., live licenses and the impact on R&D

o        Manufacturing

o        Marketing

§    Evaluate other issues potentially affecting R&D success:

o        Changes in R&D models (e.g., focus on approval in stages versus blockbuster approvals; more focus on phase II trials, etc.)

Inclusion Criteria

Hospitals Represented

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