Deliverable: Transcripts

Objectives:

• Understand current alcohol dependence treatment landscape, including the current use of Vivitrol™ (naltrexone for extended-release injectable suspension)
• Understand facilitators and barriers to use
• Estimate trends in use of Vivitrol and rationale behind expectations
• Elicit opinions on efficacy and adequacy of Cephalon educational and promotional activities

Products Highlighted:

• Vivitrol, Cephalon/Alkermes
• Campral® (acamprosate calcium), Merck Santé/Forest Laboratories
• Oral naltrexone

• Current treatment practices for alcohol dependence
• Unmet needs in treating alcohol dependence
• Awareness of Vivitrol
• Facilitators and barriers to Vivitrol use
• Estimated uptake of Vivitrol
• Potential of off-label Vivitrol use

Quotes:

• “Although acamprosate has grown the market for alcoholism medications over that for naltrexone and disulfiram, the major problem is…”
• “First line choice of medication is…”
• “The strength of acamprosate, in my opinion, is…”
• “The obvious niche for Vivitrol that I see for off-label use would be…”
• “In six months I expect to have a minimum of xx patients on Vivatrol. Vivatrol xx% Campral xx% Antabuse xx%”

Screening Criteria:

• Psychiatry, Addiction Medicine or Addiction Psychiatry – board certified
• n=8-10
• In practice between 3-35 years
• At least 50% of professional time treating patients (versus research)
• Affiliated with high-volume treatment center with an academic affiliation
• Personally see at least 20 alcohol- OR opiate-dependent patients per month
• At least 25% of substance abuse patients alcohol dependent
• Some panelists experienced using Vivitrol, either after its approval (6/13) or in clinical trials
• Not an alcohol dependence market research participant in past 3 months

Representative Institutions:

• Holyoke Hospital
• Mount Sinai
• Northtown Clinic & Mercy Hospital
• New York University Medical Center
• Pine Grove Behavioral Health
• St. Luke's Roosevelt Hospital Center
• University of North Carolina at Chapel Hill
• Kona Community Hospital
• The William J. Farley Center